Health News

Too Young Pitching Age Linked To Humeral Retrotorsion

According to a recent study, baseball pitchers with an ulnar collateral ligament injury who started pitching younger than 10 years of age…

A disease of the joints, osteoarthritis affects more than 30 million adults and is the fifth-leading cause of disability in the United States. In a new study, scientists have discovered the cellular pathway that leads to osteoarthritis and have identified a commonly used anti-depressant — paroxetine — that inhibits this pathway. The team found that Paroxetine not only slows down cartilage degeneration, but also promotes cartilage health in both mice and human cartilage in vitro. The drug may be the first-ever treatment for this debilitating, degenerative disease. Read more. Source: https://www.newswise.com/articles/common-anti-depressant-may-be-first-ever-treatment-for-osteoarthritis2

Health News

Common anti-depressant may be first-ever treatment for osteoarthritis

A disease of the joints, osteoarthritis affects more than 30 million adults and is the fifth-leading cause of disability in…

A historical asymptomatic population revealed an 18.9% prevalence of benign childhood bone tumors of the extremities, according to results. Christopher D. Collier, MD, and colleagues reviewed a historical, longitudinal radiographic collection of healthy children that included comprehensive, left-sided radiographs of the extremities at yearly intervals. A multidisciplinary panel reviewed all potential tumors and confirmed the radiographic diagnosis of each lesion, the age at which the lesion first appeared and the age at which it had resolved. Researchers calculated prevalence rates using the number of distinct patients available for each radiographic location and age. Read more. Source: https://www.healio.com/news/orthopedics/20210315/asymptomatic-children-had-a-189-prevalence-of-benign-bone-tumors

Health News

Asymptomatic children had an 18.9% prevalence of benign bone tumors

A historical asymptomatic population revealed an 18.9% prevalence of benign childhood bone tumors of the extremities, according to results. Christopher D.…

Rapamycin impairs mitochondrial function in guinea pig model By Federation of American Societies for Experimental Biology (FASEB) New research presented virtually at the American Physiological Society’s (APS) annual meeting at Experimental Biology 2021 explored the positive and negative effects of lifespan-extending drugs on mitochondrial function and age-related osteoarthritis (OA).  Decreased function of mitochondria—the energy centers of the cells—is a hallmark characteristic of aging. Maintaining mitochondrial function during the aging process while delaying age-related diseases, such as OA, could be a key to extending lifespan. Previous research has found that metformin, primarily used to treat type 2 diabetes, and rapamycin, a drug used to prevent organ transplant rejection, can extend lifespan and maintain physiological function in many animal models.  In a new study, researchers from the University of Wisconsin-Madison explored the effects of rapamycin, metformin or a regimen of both medications on a guinea pig model of OA. These drugs were chosen because they have been shown to expand lifespan and health-span through positive change in the mitochondria. The research team found that the animals treated with rapamycin and the two-drug combination had lower mitochondrial content in their muscles and the function of the mitochondria was impaired. In addition to changes in mitochondrial function, rapamycin treatment also led to a rise in blood glucose levels and worsened OA scores, a measure of disease severity. Read more. Source: https://www.newswise.com/articles/rapamycin-may-exacerbate-age-related-arthritis-despite-life-extending-benefits

Health News

Rapamycin May Exacerbate Age-related Arthritis Despite Life-extending Benefits

Rapamycin impairs mitochondrial function in guinea pig model By Federation of American Societies for Experimental Biology (FASEB) New research presented virtually…

Health News

Corrective Metacarpal Osteotomy with Intramedullary Screw Fixation: Technique and Case Report

Metacarpal malunion with significant angulation leading to symptoms from bony prominence in the palm or dorsum and decreased grip strength occur…

Health News

What I Learned at the ASSH 2020 Virtual Annual Meeting – One Hand Surgeon’s Perspective

Due to the COVID-19 pandemic, the Annual Meeting for the American Society for Surgery of the Hand (ASSH) was moved…

Health News

You Don’t Have to Postpone Your Joint Replacement During COVID-19

The COVID-19 pandemic has disrupted everyday life in many different ways. It has for some proven a big distraction, postponing…

Health News

Musculoskeletal Problems in Diabetes Mellitus

Diabetic patients may suffer from a wide range of musculoskeletal disorders that can cause pain and some dysfunctions in the…

Health News

Musculoskeletal Consequences of COVID-19

Coronavirus disease 2019 (COVID-19) is an emerging pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Epidemiological…

Health News

Mediterranean diet and risk of rheumatoid arthritis

Mediterranean diet and risk of rheumatoid arthritis: findings from the French E3N‐EPIC cohort study The Mediterranean diet (MD) has been…